Reversal of cardiac mitochondrial dysfunction

Larry H Bernstein, MD, FACP, Curator Pharmaceutical intelligence Reversal of cardiac mitochondrial dysfunction http://Pharmaceuticalintelligence.com/4_14_3013/Reversal of cardiac mitochondrial dysfunction Mitochondrial metabolism and cardiac function There is sufficient evidence to suggest that, even with optimal therapy, there is an attenuation or loss of effectiveness of neurohormonal antagonism as heart failure worsens. The production of oxygen radicals is…

Mitochondrial Disorders Overview

Mitochondrial Encephalomyopathies, Mitochondrial Myopathies, Oxidative Phosphorylation Disorders, Respiratory Chain Disorders Patrick F Chinnery, PhD, FRCPath, FRCP, FMedSci Institute of Human Genetics Newcastle University Newcastle upon Tyne, United Kingdom p.f.chinnery@newcastle.ac.uk Initial Posting: June 8, 2000; Last Update: September 16, 2010. Summary Go to: Disease characteristics. Mitochondrial diseases are a clinically heterogeneous group of disorders that arise…